Review





Similar Products

posaconazole  (Enamine Ltd)
94
Enamine Ltd posaconazole
Posaconazole, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/Posaconazole/custom%40en300-19769273%4010%2E64898%2F2026%2E07%2E30%2E741933
Average 94 stars, based on 1 article reviews
posaconazole - by Bioz Stars, 2026-09
94/100 stars
  Buy from Supplier
posaconazole  (MedChemExpress)
94
MedChemExpress posaconazole
Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, <t>posaconazole;</t> FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.
Posaconazole, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/Posaconazole/pmc13341599-158-10-25
Average 94 stars, based on 1 article reviews
posaconazole - by Bioz Stars, 2026-09
94/100 stars
  Buy from Supplier
posaconazole  (Thermo Fisher)
94
Thermo Fisher posaconazole
Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, <t>posaconazole;</t> FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.
Posaconazole, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/Posaconazole/pm42252023-81-15-30
Average 94 stars, based on 1 article reviews
posaconazole - by Bioz Stars, 2026-09
94/100 stars
  Buy from Supplier
posaconazole pos  (Tokyo Chemical Industry)
86
Tokyo Chemical Industry posaconazole pos
Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, <t>posaconazole;</t> FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.
Posaconazole Pos, supplied by Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/pos+posaconazole/pmc13194421-67-3-8
Average 86 stars, based on 1 article reviews
posaconazole pos - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
posaconazole oral suspension  (Hunan Kelun Pharmaceutical Co Ltd)
86
Hunan Kelun Pharmaceutical Co Ltd posaconazole oral suspension
Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, <t>posaconazole;</t> FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.
Posaconazole Oral Suspension, supplied by Hunan Kelun Pharmaceutical Co Ltd, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/oral+posaconazole+suspension/pmc13148035-75-14-18
Average 86 stars, based on 1 article reviews
posaconazole oral suspension - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
posaconazole d4  (MedChemExpress)
94
MedChemExpress posaconazole d4
Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, <t>posaconazole;</t> FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.
Posaconazole D4, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/Posaconazole-d4/10__1016_slash_j__microc__2026__117877-35-26-34
Average 94 stars, based on 1 article reviews
posaconazole d4 - by Bioz Stars, 2026-09
94/100 stars
  Buy from Supplier
posaconazole  (Merck & Co)
86
Merck & Co posaconazole
Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, <t>posaconazole;</t> FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.
Posaconazole, supplied by Merck & Co, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/posaconazole/10__1021_slash_acs__oprd__5c00357-239-7-14
Average 86 stars, based on 1 article reviews
posaconazole - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
lo g2 c f t ite r dupilumab amphotericin ambisome fluconazole posaconazole immunomodulators antifungals  (Gilead Sciences)
97
Gilead Sciences lo g2 c f t ite r dupilumab amphotericin ambisome fluconazole posaconazole immunomodulators antifungals
Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, <t>posaconazole;</t> FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.
Lo G2 C F T Ite R Dupilumab Amphotericin Ambisome Fluconazole Posaconazole Immunomodulators Antifungals, supplied by Gilead Sciences, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/posaconazole/AmBisome/pm41778809-196-54-63
Average 97 stars, based on 1 article reviews
lo g2 c f t ite r dupilumab amphotericin ambisome fluconazole posaconazole immunomodulators antifungals - by Bioz Stars, 2026-09
97/100 stars
  Buy from Supplier

Image Search Results


Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, posaconazole; FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.

Journal: Frontiers in Microbiology

Article Title: In vitro synergistic activity of betulinic acid combined with azoles against pathogenic fungi

doi: 10.3389/fmicb.2026.1835794

Figure Lengend Snippet: Summary of drug interaction for the combination of BA and azoles. (A) Species–specific summary of interactions between BA–azole combinations and pathogenic fungi. (B) Azole–specific summary of interactions between BA–azole combinations and pathogenic fungi. (C) Isobologram analysis of the synergistic interaction between BA and POS. The X-axis represents normalized POS concentration, and the Y-axis represents normalized BA concentration. Normalized concentration was calculated as the MIC of the drug in combination divided by the MIC of the drug alone. The solid diagonal line represents the theoretical additive effect based on the Loewe additivity model. The upper and lower dashed lines indicate the 95% confidence intervals of the additive line. Each symbol corresponds to a different clinical isolate. Data points located below the lower 95% confidence line indicate synergistic activity. S, synergy (FICI≤0.5); I, indifference (FICI from >0.5 to ≤4); A, antagonism (FICI of >4); BA, betulinic acid; ITR, itraconazole; VOR, voriconazole; POS, posaconazole; FLC, fluconazole. The synergism rate was calculated by dividing the number of strains exhibiting synergism by the total number of strains tested.

Article Snippet: The experimental drugs, such as ITR (HY–17514, purity = 99.59%), posaconazole (POS, HY–17373, purity = 99.95%) and BA (HY–N1451, purity = 98.77%), were obtained from MedChemExpress (MCE), NJ, USA.

Techniques: Concentration Assay, Activity Assay

(A–Q) Detection of ROS levels after combined treatment with BA and POS; (R–U) Detection of ROS levels after combined treatment with BA and ITR. One–way ANOVA followed by Tukey’s HSD test was used for multiple group comparisons. POS, posaconazole; BA, betulinic acid; ns, p > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Journal: Frontiers in Microbiology

Article Title: In vitro synergistic activity of betulinic acid combined with azoles against pathogenic fungi

doi: 10.3389/fmicb.2026.1835794

Figure Lengend Snippet: (A–Q) Detection of ROS levels after combined treatment with BA and POS; (R–U) Detection of ROS levels after combined treatment with BA and ITR. One–way ANOVA followed by Tukey’s HSD test was used for multiple group comparisons. POS, posaconazole; BA, betulinic acid; ns, p > 0.05; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.

Article Snippet: The experimental drugs, such as ITR (HY–17514, purity = 99.59%), posaconazole (POS, HY–17373, purity = 99.95%) and BA (HY–N1451, purity = 98.77%), were obtained from MedChemExpress (MCE), NJ, USA.

Techniques: